| 0. | 19.06.2021 | SG Groß Gaglow (A) | 0:9 | 2 | - | - | |
| 0. | 03.07.2021 | Brandenburger SC Süd 05 (H) | 9:0 | - | - | x | |
| 0. | 11.07.2021 | SV Lichtenberg 47 (A) | 1:3 | 1 | - | x | |
| 0. | 17.07.2021 | TSV Havelse 1912 (A) | 1:1 | - | - | x | |
| 1. | 25.07.2021 | FSV 63 Luckenwalde (H) | 1:1 | - | - | x | |
| 2. | 28.07.2021 | BFC Dynamo (A) | 2:1 | - | - | x | |
| 3. | 02.08.2021 | FSV Optik Rathenow (H) | 1:0 | 1 | - | x | |
| 0. | 06.08.2021 | Offenbacher FC Kickers 1901 (H) | 1:1 | - | x | - | |
| 5. | 14.08.2021 | VfB Auerbach 1906 (H) | 5:0 | - | - | x | |
| 7. | 21.08.2021 | FSV Union Fürstenwalde (H) | 6:1 | 1 | - | x | |
| 11. | 20.10.2021 | Chemnitzer FC (A) | 1:1 | - | x | - | |
| 15. | 24.10.2021 | SV Tasmania Berlin (A) | 2:1 | - | - | x | |
| 4. | 27.10.2021 | FC Carl Zeiss Jena (A) | 0:1 | - | x | - | |
| 16. | 31.10.2021 | SV Babelsberg 03 (H) | 2:0 | - | x | - | |
| 0. | 12.01.2022 | SV Wacker 09 Cottbus-Ströbitz (H) | 6:0 | 1 | x | - | |
| 0. | 21.01.2022 | Hertha BSC II (H) | 2:1 | - | x | - | |
| 23. | 29.01.2022 | FC Carl Zeiss Jena (H) | 0:1 | - | x | - | |
| 24. | 05.02.2022 | VfB Auerbach 1906 (A) | 0:2 | - | x | - | |
| 26. | 20.02.2022 | FSV Union Fürstenwalde (A) | 2:2 | - | - | x | |
| 27. | 26.02.2022 | Berliner AK 07 (H) | 1:0 | - | x | - | |
| 28. | 06.03.2022 | VSG Altglienicke (A) | 3:0 | - | x | - | |
| 30. | 20.03.2022 | Chemnitzer FC (H) | 0:1 | - | x | - | |
| 6. | 26.03.2022 | SV Babelsberg 03 (H) | 2:0 | - | x | - | |
| 25. | 30.03.2022 | Tennis Borussia Berlin (H) | 2:2 | - | x | - | |
| 31. | 03.04.2022 | FC Eilenburg (A) | 1:1 | - | x | - | |
| 35. | 23.04.2022 | SV Babelsberg 03 (A) | 0:2 | - | x | - | |
| 36. | 01.05.2022 | SV Lichtenberg 47 (H) | 4:1 | - | x | - | |
| 37. | 08.05.2022 | Hertha BSC II (A) | 1:1 | - | x | - | |
| 38. | 15.05.2022 | BSG Chemie Leipzig (H) | 4:1 | - | x | - | |
